Depuy Synthes

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3D printed cellular titanium implants that feature 80% porous macro-, micro- and nanostructures, are designed to mimic cortical and cancellous bone.1,2

 

BONE-MIMICKING CELLULAR TITANIUM MATERIAL – Cellular structure of the material is designed to mimic the published properties of bone.

 

EXCELLENT VISUALIZATION – Ability to clearly visualize the cage intra- and post-operatively on imaging modalities without interference3,4

 

TARGETED MODULUS OF ELASTICITY – Modulus of Elasticity similar to cancellous bone (Figure 1)5,6

Features & Benefits

MACROSTRUCTURE

Surface roughness has been shown to have a beneficial effect on cell differentiation and proliferation in in-vitro studies of osteoblast-like cells cultured on similar roughened titanium materials7,8

MICROSTRUCTURE

In-vitro studies have reported greater osteoblastic differentiation in human stem cells cultured on similar porous titanium constructs compared to solid titanium surfaces9

  • In-vivo studies with similar porous titanium materials show that bony in-growth is increased at the 500-700 μm pore size range compared to larger or smaller pores10-12
  • The porosity of cancellous human bone is typically 50-90%13
  • Based on this published science, CONDUIT™ Implants are designed with 80% porosity and 700 μm pore size2,14

NANOSTRUCTURE

Similar titanium materials with nanoscale features have shown in in-vitro studies to lead to increased osteoblast adhesion when compared to conventional titanium materials15

  • All CONDUIT Implants undergo acid etching and heat treatment to promote micro-and nanoscale surface roughness1

EXCELLENT VISUALIZATION

Ability to clearly visualize the cage intra-and post-operatively on imaging modalities without interference3,4

80% porosity2:

  • High radiographic visibility allows for better contouring, endplate-implant contact evaluation and absence of tantalum marker scattering intra-and post-operatively
  • Clear visualization of the implant on X-Ray, absence of scattering on CT Scan and diminished artifacts in MRI3,4

TARGETED MODULUS OF ELASTICITY

Modulus of Elasticity similar to cancellous bone5,6 Proprietary 3D printing technology leads to cellular design that offers Modulus of Elasticity of titanium similar to bone5

  • Highly porous surface area and implant footprint variety that allows for maximum endplate-implant contact16